Teprotumumab injection

What is this medicine?

TEPROTUMUMAB (tep roe toom ue mab) is used to treat thyroid eye disease.

How should I use this medicine?

This medicine is for infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • signs and symptoms of high blood sugar such as dizziness; dry mouth; dry skin; fruity breath; nausea; stomach pain; increased hunger; increased thirst; increased urination

  • stomach pain, diarrhea

  • trouble hearing

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • changes in taste

  • hair loss

  • headache

  • muscle spasms

  • unusually weak or tired

What may interact with this medicine?

Interactions have not been completed.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • diabetes

  • inflammatory bowel disease

  • an unusual or allergic reaction to teprotumumab, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your health care professional for regular checks on your progress. Tell your health care professional if your symptoms do not start to get better or if they get worse.

Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their health care professional if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects and harm to an unborn child. Talk to your health care professional for more information.

If you notice an increased hunger or thirst, different from your normal hunger or thirst, or if you find that you have to urinate more frequently, you should contact your health care professional as soon as possible. You may need to have your blood sugar monitored. This medicine can cause changes in your blood sugar levels. You should monitor your blood sugar more frequently if you have diabetes.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2020 Elsevier